28 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Syndrome - Diagnosis ... and Management ... vonWillebrand #Syndrome ... #treatment #hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... underlying hematologic disorders ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... Orange or Hep C Clinical ... lymphoproliferative disorders ... microglobulin Treatment ... • Richter’s Syndrome
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Overview: • Most common ... leukemia in adults • Disorder ... immunophenotype Clinical ... routine CBC (rnost common ... hemeonc #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... to 8 years Clinical ... severe community-acquired ... : • Nephrotic syndrome
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... symptoms - most common ... malignancies -> CLL ... hemolytic #anemia #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... relatives (if all ... bleeding tendency is acquired ... Marfan syndrome, ... osteogenesis imperfecta
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... APML #diagnosis #management ... #hematology #oncology
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV

Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
99: Serotonin Syndrome ... Hyperthermia (most common ... Diagnosis: Clinical ... Cornerstone of treatment ... SerotoninSyndrome #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Most common cytopenia ... Neutropenia • Platelet Disorders ... factor (GCSF) treatments ... #diagnosis #hematology