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Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Hemolytic Anemia Intrinsic ... Causes: • Enzyme ... elliptocytosis Extrinsic Causes ... Intravascular Causes ... classification #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
affected in the intrinsic ... Causes include : ... Pre-analytical cause ... aPTT #Prolonged #Causes ... #differential #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Transfusion reaction • Intrinsic ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Congenital intrinsic ... Pre-analytical cause ... aPTT #Prolonged #Causes ... #differential #hematology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
extrinsic and intrinsic ... Initiation phase caused ... dependent upon intrinsic ... diagnosis #models #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Abnormality in the intrinsic ... pathway to the intrinsic ... discern these causes ... Differential #Diagnosis #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... Infiltration: • Hematologic ... and non-hematologic ... Diagnosis #Algorithm #Causes ... #Hematology
Simplified Coagulation Cascade and Differential Diagnosis #Coagulation #Cascade #Differential #Diagnosis #Intrinsic #Extrinsic #Pathway #Hematology
Differential #Diagnosis #Intrinsic ... Extrinsic #Pathway #Hematology
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis #causes
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Nodosum #Mnemonic #Causes ... Differential #Diagnosis #Dermatology
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