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causes hematology injury anemia lfts management transaminitis classification ddxof em gastroenterology hypocalcemia mcv thrombocytosis aclf aflp approach ascites bilateral blood
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Diagnosis Framework ... Cirrhosis • Chronic ... Hepatopathy • Acute ... (>1000): • DILI ... #Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... #Chronic #Liver ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Diagnosis Algorithm ... • Iatrogenic: DILI ... #diagnosis #algorithm ... #hepatology
Differential Diagnosis of Pedal Edema #Diagnosis #EM #IM #Edema #LowerExtremity #Differential #Unilateral #Bilateral #Acute #Chronic #Algorithm
Differential Diagnosis ... of Pedal Edema #Diagnosis ... #EM #IM #Edema ... Unilateral #Bilateral #Acute ... #Chronic #Algorithm
Hypocalcemia Differential Diagnosis Algorithm - Magnesium deficiency - Hypoparathyroidism - Hypoalbuminemia (Pseudohypocalcemia) - Vitamin D
Diagnosis Algorithm ... deficiency - Acute ... or chronic kidney ... #Algorithm #endocrinology ... #differential
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
Differential Diagnosis ... vs. chronic) 2) ... history (cardiac, liver ... #EM #IM #Nephro ... #Algorithm #Ddxof
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Renal Disease, Liver ... #Diagnosis #Algorithm ... #Causes #Hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
> 2 • NASH, Chronic ... injury: > 3 • Chronic ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
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