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hematology management blood differential product rash reactions skinrash syndrome activation antimda5 antimda5dm arterial behcet blastomycosis canimorsus capnocytophaga causes cellulitis coagulation
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... purple, hemorrhagic skin ... deficiency • Liver ... #Differential #Diagnosis ... #hematology #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... Differential Diagnosis ... #rash #diagnosis ... #rheumatology
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Blastomycosis Skin ... Lives in an old ... Diagnosis? ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
+purpuric rash → ... purpura fulminans ... the key to the diagnosis ... #Rash #dermatology ... #clinical #photo
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Testosterone - Coumadin skin ... Syndrome, Ischemic Liver ... other causes of purpura ... pathophysiology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(Petechial or purpuric ... thrombocytopenia • Liver ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Clinical ... necrosis • Purpura ... : • + Clinical ... #rheumatology # ... hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Petechiae • Purpura ... DIC • Severe Liver ... #Coagulation #diagnosis ... treatment #management #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... lesions, palpable purpura ... Behcet syndrome (Clinical ... inhibitors • Uveitis- Ophthalmology ... signs #symptoms #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... disease and ILD • Liver ... Liver biopsies show ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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