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diagnosis differential dili transaminitis drug gastroenterology hepatitis idiosyncratic interpretation management rvalue
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... #Liver #Injury ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury → liver ... Liver Injury Differential ... #Liver #Injury ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... alternative causes • Hepatocellular ... hepatitis #DILI #DrugInduced ... #Liver #Injury ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... ALP) • R > 5: Hepatocellular ... #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
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