11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... Pregnancy (AFLP) ... child * Severe cases ... failure * Responds ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
child * Severe cases ... failure * Responds ... #AFLP #Obstetrics ... #OBGyn #Hematology ... Diagnosis #Comparison #Table
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Acute #Liver # ... Injury #Causes # ... #Failure
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... liver failure rapidly ... Preeclampsia, HELLP ... Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... Pregnancy (AFLP) ... failure with coagulopathy ... #hepatology #obstetrics ... #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... of Acute Liver ... : HELLP • Iatrogenic ... intestines, white blood
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... Liver Failure ( ... injury < 26 weeks ... intestines, White blood ... #differential #Hepatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
An acute rise or ... with previously stable ... papilledema, heart failure ... kidney injury). ... Pregnancy-associated
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... hypoTN, renal failure ... Transfusion Related Acute ... Lung Injury (TRALI ... eruptions, diarrhea, liver