13 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... infection. ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... parvovirus B19 infection ... Antiphospholipid-antibody syndrome ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Bacterial or viral infection ... Cardiomyopathies - Viral infection ... #pain #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Autoimmune Rheumatologic ... arthritis • SLE ... Symmetrical: • RA • SLE ... #Diagnosis #MSK ... #rheumatology #
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... Unexplained fever, when infection ... including in children (pediatric ... erythematosus #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Fever/Chills/Joint ... pain/Night sweats ... arthritis - SLE ... Seronegative Reactive Syndrome ... differential #diagnosis #msk
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, fever, joint pain ... , bleeding, infections ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
+/- myocardial infarction ... Oral aphthae : SLE ... inhibitors • Uveitis- Ophthalmology ... Nonsurgical abdominal pain ... signs #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... vesicular eruption • Joints ... tract: Abdominal pain ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology