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diagnosis vasculitis cryoglobulinemia cryoglobulins differential erythematosus hcq hydroxychloroquine levels measurement pharmacology polychondritis relapsing serum summary systemic types vasculitides
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... Hydroxychloroquine *Short ... Summary #diagnosis #rheumatology ... #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... if < 200ng/mL Best ... #rheumatology # ... pharmacology #levels #lupus ... #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... • They can cause ... (e.g. systemic lupus ... diagnosis #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... retinopathy Lab Tests ... vasculitis, and SLE ... differential #diagnosis #rheumatology ... #classification
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
polychondritis usually spares ... such as: • SLE ... Diagnosis: • Clinical tests ... Polychondritis #rheumatology ... #diagnosis #management
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