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diagnosis causes management hyperkalemia treatment acidosis algorithm alkalosis chloride criticalcare elevation gitelman high hypokalemia k lactic metabolic pathophysiology rhabdomyolysis shock
Shock Classification and Differential Diagnosis SHOCK • MAP <65, SBP <90, drop in SBP > 40 •
Shock Classification ... and Differential ... malperfusion • Lactate ... Medications, Spinal Cord Injury ... Diagnosis #Types
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... excretion (e.g., urine ... liver or renal injury ... LV failure - Low ... #typeb #classification
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal/low ... sodium is typically ... and potassium acid ... #Algorithm #nephrology ... #differential #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Weakness - Dark urine ... Isotonic fluid/Lactated ... Monitor potassium ... causes #treatment #nephrology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
neuromuscular injury ... Drug-associated: heparin, low-molecular-weight ... #Hyperkalemia #Differential ... Diagnosis #High #Potassium ... #Classification
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... Hypocalciuria (spot urine ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, rhabdo/crush injury ... Aldosterone, RTA Type ... lysis) ± Urine ... acidosis) • Low ... #nephrology #K
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