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diagnosis treatment algorithm differential hepatology neurology aki indications causes infectiousdiseases kidney lfts pharmacology shock summary toxicology transaminitis ards blastomycosis blood
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... #Chronic #Liver ... Cirrhosis #Hepatology #gastroenterology ... #management #diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... differential #Diagnosis #Management ... #gastroenterology ... #algorithm #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... > 2 • NASH, Chronic ... > 3 • Chronic
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Mixed - Check Acute ... injury < 26 weeks ... > 2 • NASH, Chronic ... muscle injury: ... > 3 • Chronic
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Cirrhosis • Chronic ... Hepatopathy • Acute ... (Drug-induced liver ... injury) • Ischemic
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... involvement, Kidney injury ... dechallenge • Acute ... or chronic atypical ... e.g. ascites), Chronic
Hypernatremia Management Algorithm Acute vs Chronic Calculate Losses • Current water Deficit • Ongoing Free water Losses •
Hypernatremia Management ... Algorithm Acute ... vs Chronic Calculate ... Hypernatremia #Management ... Algorithm #treatment #nephrology
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... disease - Acute ... #Kidney #Injury ... Classification #diagnosis #nephrology
IDEAL-ICUTrial - Visual Abstract Is there an ideal time to start Renal Replacement Therapy (RRT) in patients
patients with Acute ... Kidney Injury ( ... Kidney Injury, ... VisualAbstract #Nephrology ... #EBM #RRT #CriticalCare
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... 5-10x normal - Chronic ... #Patterns #Liver
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