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diagnosis hepatology liver algorithm differential dili aclf acute aih bpap cirrhosis common cpap cvid drug druginduced failure hematology hypogammaglobulinemia idiosyncratic
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... underlying liver disease ... Drug-Induced Liver Injury ... #ACLF #Acute #Chronic ... Cirrhosis #Hepatology #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
• Autoimmune: ... Autoimmune hepatitis ... > 2 • NASH, Chronic ... viral hepatitis ... : > 3 • Chronic
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Alcohol-related liver disease ... e.g. ascites), Chronic ... hepatitis fibrosis ... steatosis • Autoimmune ... hepatitis #DILI
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... from subclinical disease ... - Symptoms of chronic ... pattern of liver injury ... (eg Viral) Management
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... symptoms of liver disease ... #gastroenterology ... #algorithm #gastroenterology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... and hepatitis ... : Pneumonia • Autoimmune ... and M panel Management ... Malignancies • Chronic
Chronic Pancreatitis Definition: A pathologic fibroinflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other
Chronic Pancreatitis ... to parenchymal injury ... Genetic) • A (Autoimmune ... Pancreatitis #diagnosis #management ... #gastroenterology
Noninvasive Positive Pressure Ventilation (NIPPV) Expiratory & Inspiratory Positive Airway Pressure Both increase intrathoracic pressure, which can decrease
neuromuscular disease ... often w/ acute on chronic ... pneumothorax. esophageal injury ... #indications #criticalcare ... #management
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