10 results
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop diuretics ... #Pharmacology # ... nephrology #conversion
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... Spironolactone MCW Nephrology ... MCW_Nephrology #diuretics ... #pharmacology # ... Pharmacokinetics #halflife #comparison
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Increased plasma insulin ... thiazide-like diuretics ... , Osmotic diuresis ... Hypokalemia #Causes #differential ... #diagnosis #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Intracellular Shift • Insulin ... Diuretics (discontinued ... #Hypokalemia #Differential ... Causes #Workup #Nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
agonists - Insulin ... foscarnet - Diuretics ... and other loop diuretics ... #Medications #differential ... #diagnosis #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Hypophosphatemia - Differential ... stimulation, TPN, Insulin ... Inh., Osmotic diuresis ... Hypophosphatemia #Differential ... Workup #phosphate #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Administration of inulin ... Urine Cl - Loop diuretics ... , Thiazide diuretics ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • K sparing diuretics ... paralysis - Insulin ... #hyperkalemia #differential ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • K sparing diuretics ... paralysis - Insulin ... #hyperkalemia #differential ... potassium #high #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Hypokalemia - Differential ... Transcellular shift • Insulin ... contracted • Loop diuretics ... #Hypokalemia #Nephrology ... #Differential #