11 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential # ... hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... ALP: - Enzymes ... • Liver (80%) ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
ALP enzyme- Discovered ... synthesized in: liver ... Adult form: Less ... Low ALP in adult ... Hyophosphatasia #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
the magnitude of enzyme ... ALP, alkaline phosphatase ... aminotransferase; BMI, body ... #Liver #Enzymes ... #Differential #
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Diagnosis Ferritin ... be used by the bone ... is made in the liver ... HLH or Adult Onset ... Hematologic Malignancy
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Enzyme Elevation ... hemolysis) • ALP: Bone ... #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Epidemiology: young adults ... the spleen or liver ... Diagnosis of B-Symptoms ... #differential # ... hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Enzyme Elevation ... hemolysis) • ALP: Bone ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... (elevations of liver ... enzymes, diarrhea ... ) - Bone Marrow ... NTM #Infections #differential
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... - Elevated liver ... enzymes - Coagulopathy ... Hemophagocytosis in bone ... #Management #Hematology