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management infectiousdiseases differential hiv neurology pulmonary syndrome toxicity amiodarone arteritis cns encephalopathy ferrous fungal gca giantcell induced iron mycobacteria mycoses
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
GAS in 30% of cases ... 50% in nec fasc Diagnostic ... kidneys, liver, lung ... /ARDS, coagulopathy ... day 2 + 3 BIDMC Infectious
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... treatment is generally required ... Demyelinating disease caused ... #AIDS #opportunistic
Acute Iron Poisoning There are five classically described phases of toxicity: Gastrointestinal phase (~6 hours post-ingestion) -
Abdominal pain, nausea ... post-ingestion) - Symptom ... deterioration Shock ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Complex (MAC): • Acquired ... gastrointestinal symptoms ... Diagnosis Of NTM ... • Clinical (Symptoms
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Rheumatologic symptoms ... yeast • At risk: AIDS ... change in the lungs ... fever • Septic shock ... nails, bronchi, lungs
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... - Differential Diagnosis ... Constitutional symptoms ... factor • May cause ... #AIDS #pulmonary
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
organizing pneumonia, ARDS ... gradually with symptoms ... failure - Infectious ... Improvement in symptoms ... #management #Toxicology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... Neurological symptoms ... : • Infection, ... the underlying cause ... until cause identified
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis vs infection ... identifies 85 to 95% of cases ... day, followed by long ... absence of visual symptoms ... Temporal #Signs #Symptoms
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