11 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Shock and Vasoactive ... Arrhythmias / CHB ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... diagnosis #management #comparison
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
: Distributive shock ... , Shock where ↑ ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Demystified Shock ... Vasopressors #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... in refractory shock ... Inotropes #management #criticalcare ... #summary #comparison ... #table #pharmacology
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors #Inotropes #criticalcare ... #pharmacology # ... comparison #shock
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... celiac disease, CF ... Acute DIC - Septic shock ... Summary #table #comparison
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Clinical Management ... Common Causes of Shock ... HEMORRHAGIC SHOCK ... • Consider intraaortic ... #CriticalCare
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
just simply a clinical ... essentially Cardiogenic Shock ... #heartfailure #chf ... #criticalcare # ... icu #clinical #pharmacology
GLP-1 Medications: Ozempic vs. Trulicib (semaglutide vs. dulaglutide) 

From my experience, Ozempic and Trulicity are the
However, clinical ... have ASCVD or HF ... #dulaglutide #Pharmacology ... #Diabetes #Comparison
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
CSF Penetration ... treatment of community-acquired ... successfully in clinical ... infections 5 however clinical ... InfectiousDiseases #Pharmacology