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management hematology differential oncology algorithm infectiousdiseases syndrome syndromes activation adultonset cancer capillary causes chronic clarksons classification cll disorders fungal fusarium
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... : • Infectious ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... • Autoimmune diseases ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... procedures - Infection ... #Causes #Workup ... #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... mononeuritis multiplex WORKUP ... confirm DAH, r/o infection ... #management #treatment
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
Acquired through ... Refractory FUO, Sino-pulmonary ... : • Optimal treatment ... Diseases Fellows ... infectiousdiseases #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... filling +++ (risk of pulmonary ... of infections) ... leak #syndrome #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... number of sites of disease ... Hodgkin Lymphoma Treatment
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