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management treatment coagulation anorexianervosa arterial biliary bullous cholangitis cirrhosis comparison complications deficiencies deficiency dic differential disseminated embolism hemophagocytic hepatology hlh
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... of Factor IX Acquired ... Acute DIC - Septic shock ... table #comparison #diagnosis ... #hematology #deficiency
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
and Management Summary ... Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #Management #dermatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management Summary ... present, symptoms, signs ... with evidence of acquired ... #Management #Summary ... #treatment #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... THROMBOSIS • Acquired ... Venous #Arterial #pathophysiology ... #hematology #differential ... #diagnosis #vascular
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Purtilo (XLP) Acquired ... Drugs, Unknown cause ... management #treatment #summary ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) - Summary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... #workup #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... dysfunction (16%) • Shock ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
and memory loss HEMATOLOGIC ... hypogonadism - acquired ... risk of fracture DERMATOLOGIC ... Complications #pathophysiology ... #diagnosis #signs
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