83 results
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Framework Diagnosis ... Immunocompromise Treatment ... • Secondary to Treatment ... diff) • Hospital-Acquired
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Purtilo (XLP) Acquired ... Drugs, Unknown cause ... Treatment: • ... #management #treatment
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
hemorrhagic rash; symptoms ... of shock • Mumps ... widespread infection ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Functional Dyspepsia - Signs, Symptoms and Pathophysiology
Delayed gastric emptying - Postprandial fullness, nausea, vomiting
Hypersensitivity to gastric
Dyspepsia - Signs, Symptoms ... and Pathophysiology ... loss H. pylori infection ... gastroenterology #symptoms ... #diagnosis #signs
Hordeolum vs Chalazion

Hordeolum (Stye):
 • Location: Most commonly found at or near an eyelash follicle
 •
eyelash follicle • Cause ... : Bacterial infection ... of the lids • Symptoms ... upper lid • Cause ... #Clinical #Diagnosis
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
Anaplasma Infection ... phagocytophilum Pathophysiology ... morulae Signs and symptoms ... #Anaplasma #Infection ... #diagnosis #microbiology
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
GAS in 30% of cases ... 50% in nec fasc Diagnostic ... necrosis STSS Treatment ... day 2 + 3 BIDMC Infectious ... #management #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... can be community-acquired ... Ileus, Megacolon, Shock
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... drug reaction, infection ... glucocorticoid treatment ... #Differential #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... pylori test (GI symptoms ... evaluation: not required ... #Differential #Diagnosis