40 results
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... When present, symptoms ... with evidence of acquired ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... Purtilo (XLP) Acquired ... Unknown cause Treatment ... #management #treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... can be community-acquired ... Ileus, Megacolon, Shock
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... : • Recurrent infections ... Symptomatic anemia Diagnosis ... #management #treatment ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... drug reaction, infection ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... cells per μL • Diagnosis ... Antimicrobial treatment ... is generally required ... #differential #diagnosis
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dog or cat bite. symptoms ... endocarditis, sepsis, shock ... abrupt onset of symptoms ... the key to the diagnosis ... Canimorsus #Skin #Rash #dermatology
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
cold exposure, infection ... and menses • Pathophysiology ... thyroid hormone • Symptoms ... or high T3 • Treatment ... Periodic #Paralysis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
HLH signs and symptoms ... can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... #hematology