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management neurology infectiousdiseases differential syndrome aids 1 apml associated barre cdi cdiff clostridioides clostridium cns dementia differentiation difficile disorder encephalopathy
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Diagnosis Framework ... cells per μL • Diagnosis ... Antimicrobial treatment ... is generally required ... #differential #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Perforation) Pathophysiology ... can be community-acquired ... Ileus, Megacolon, Shock ... Bezlotoxumab 10 mg/kg IV
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... early stages of infection ... • Depressive symptoms ... Diagnosis: MRI ... Treatment: • HAART
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
immunodeficiency virus (HIV ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT ... ventilation is required
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Complex (MAC): • Acquired ... gastrointestinal symptoms ... Diagnosis Of NTM ... • Clinical (Symptoms ... • Microbiologic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... : Infection (sepsis ... • Steroids: IV
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... Etiology: • Pathophysiology ... Neurological symptoms ... : • Infection, ... epilepticus Treatment
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... simplex virus, HIV ... Transverse Myelitis Treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
acute respiratory symptoms ... Chronic pulmonary symptoms ... Rheumatologic symptoms ... Aspergillosis Pathophysiology ... fever • Septic shock
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