14 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Acute DIC - Septic shock ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... symptoms - Headache, fever ... , Hypotension, shock ... #rheumatology # ... comparison #table
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... syndromes Clinical ... is the main clinical ... Activation #Syndrome #Diagnosis ... #Rheumatology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
suspicion is required ... for diagnosis! ... features: Fever ... features: Fever ... #table
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... Purtilo (XLP) Acquired ... treatment #summary #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... explain symptoms • Fever ... pulmonary edema) • Fever ... #diagnosis #comparison ... #table
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... mucus, Abd pain, Fever ... Toxic Megacolon, Shock ... can be community-acquired ... Ileus, Megacolon, Shock
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... tachycardia or fever ... likelihood of negative clinical ... hypotension or septic shock ... neutrophil #WBC #CBC #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... - Differential Diagnosis ... Algorithm Structural ... Bacteremia/Septic Shock ... #Hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
diagnosis but rather ... establishing a diagnosis ... essentially Cardiogenic Shock ... #algorithm #management ... cardiology #treatment #table