13 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Hemophilia A - Deficiency ... of Factor IX Acquired ... Acute DIC - Septic shock ... Deficiencies #Summary #table ... #comparison #diagnosis
Myocarditis
Diagnosis 
• Endomyocardial biopsy (gold standard, rarely performed) 
• Clinical presentation 
• Cardiovascular MRI 
Clinical 
•
Myocarditis Diagnosis ... performed) • Clinical ... Cardiovascular MRI Clinical ... Abnormal ECG, echocardiogram ... • Cardiogenic shock
Pulmonary Embolism - Risk Stratification and Prognostication based on scores and clinical features

 • Bova score
on scores and clinical ... Hemodynamics (Stable ... Transient Hypotension, Shock ... prognostication #diagnosis ... #management #stratification
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
and Management ... GrepMed Handbook Clinical ... Toxic Megacolon, Shock ... can be community-acquired ... Ileus, Megacolon, Shock
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Purtilo (XLP) Acquired ... Cellular immune deficiency ... #management #treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Scurvy (Vitamin C Deficiency ... ) - Diagnosis and ... Management Vitamin ... C is required for ... poor nutrition Clinical
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... dysfunction (16%) • Shock ... thrombopoietin deficiency ... #Coagulation #diagnosis ... causes #treatment #management
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
oxoprolinase • Acquired ... pregnancy (glycine deficiency ... high index of clinical ... Oxoprolinuria #diagnosis ... #management #treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
diagnosis but rather ... establishing a diagnosis ... essentially Cardiogenic Shock ... #algorithm #management ... cardiology #treatment #table
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Clinical • Under-recognized ... Pts: cardiogenic shock ... Delivery • Stable ... Cardiomyopathy #diagnosis