15 results
Antibiotics for severe community-onset pneumonia 

Atypical coverage always 

- Usually azithromycin 500 mg daily 

- Doxycycline
severe community-onset ... piperacillin-tazobactam Septic Shock ... #Acquired #Pneumonia ... #CAP #Antibiotics ... #Coverage #Management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Cardiogenic: Myocardial Infarction ... Decompensated CHF ... Abdominal compartment syndrome ... : 1) MAP > 60-65 ... #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... post-ABx, but can ... be community-acquired ... 10 mg/kg IV x 1
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... -> 40 years • Can ... frequent and severe community-acquired ... : • Nephrotic syndrome
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... Diagnosis and Management ... Egophony (May appear 1- ... 96.1% • Empiric antibiotic ... #Community #Acquired
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
of community-acquired ... compared to other antibiotic ... classes. 1 only ... in clinical CNS infections ... of CNS infections
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1- ... response preceding infection ... main variants: (1) ... #diagnosis #management ... #treatment #neurology
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
appear in 1-2 days ... 1. ... progressive inflammatory infection ... - Antibiotic ... #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... and cauda equina TREATMENT ... ventilation is required ... Guillain #Barre #Syndrome ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
/Sepsis/Shock, Autoimmune ... PRES Diagnosis: 1. ... Diagnosis: • Infection ... epilepticus Treatment ... #diagnosis #management