12 results
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Adjuvant therapies ... diseases - Severe Community ... Acquired Pneumonia ... SCAP severe community-acquired ... Pharmacology #Management #Treatment
Community Acquired Pneumonia - Severity and Prognosis
Criteria for Severe CAP - Severe CAP present in 1
Community Acquired ... CAP present in 1 ... criteria: Septic shock ... EricsMedicalLectures/ #CAP #Community ... #Acquired #Pneumonia
Community Acquired Pneumonia - Presenting Features
 • History in favor of CAP: Dyspnea, Cough, particularly if
Community Acquired ... complicated by septic shock ... CAP present in 1 ... criteria: Septic shock ... #Acquired #Pneumonia
Antibiotic treatment durations for first line antibiotics recommended by Public Health England (PHE) guidance
 • Acute
Antibiotic treatment ... acquired pneumonia ... CRB65=0 7 days • Community ... acquired pneumonia ... and CRB65=1 7-10
Antibiotics for severe community-onset pneumonia 

Atypical coverage always 

- Usually azithromycin 500 mg daily 

- Doxycycline
Antibiotics for severe community-onset ... piperacillin-tazobactam Septic Shock ... Hospitalization for > 1 ... - Linezolid 1 ... #Acquired #Pneumonia
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... post-ABx, but can be community-acquired ... Ileus, Megacolon, Shock ... 10 mg/kg IV x 1
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... possible w/ early shock ... SOFA and SIRS 1) ... IV's, Consider IL NS ... #criticalcare #treatment
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
documenting successful treatment ... of community-acquired ... antibiotic classes. 1 ... FDA-approved for UTI treatment ... outcomes when used in treatment
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... chest pain (LR + NS ... Egophony (May appear 1- ... #Pulmonary #Community ... #Acquired
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... cytokines, such as IL-1 ... nervous system (CNS ... Treatment: • Corticosteroids