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management cap pharmacology pneumonia diagnosis infectiousdiseases outpatient cdi cdiff clostridioides clostridium cns coverage csf days difficile durations gastroenterology guidelines infection
Outpatient Treatment of with Community-Acquired Pneumonia (CAP) No comorbidities or risk factors for MRSA or Pseudomonas aeruginosa:
Outpatient Treatment ... of with Community-Acquired ... fluoroquinolone #IDSA ... #Acquired #Pneumonia ... #Antibiotics #Treatment
Antibiotic treatment durations for first line antibiotics recommended by Public Health England (PHE) guidance • Acute
Antibiotic treatment ... acquired pneumonia ... CRB65=0 7 days • Community ... acquired pneumonia ... and CRB65=1 7-10
Antibiotics for severe community-onset pneumonia Atypical coverage always - Usually azithromycin 500 mg daily - Doxycycline
severe community-onset ... piperacillin-tazobactam Septic Shock ... Hospitalization for > 1 ... - Linezolid 1 ... #Acquired #Pneumonia
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... post-ABx, but can be community-acquired ... Ileus, Megacolon, Shock ... 10 mg/kg IV x 1
CSF Penetration of Antimicrobials Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
Penetration of Antimicrobials ... of community-acquired ... compared to other antibiotic ... classes. 1 only ... Penetration #CNS #Antimicrobials
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Community Acquired ... Egophony (May appear 1- ... 96.1% • Empiric antibiotic ... procalcitonin level Treatment ... #Pulmonary #Community
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