15 results
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... acidosis: Gl tract ... acidosis: Proximal ... Algorithm #causes #potassium
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Non-anion Gap Metabolic ... Hypokalemia ... Potassium-sparing ... aniongap #NonGap #Metabolic ... #Acidosis #differential
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... Pressure: - Metabolic ... acidosis: Proximal ... diagnosis #Algorithm #differential ... #potassium #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... infusions) - Metabolic ... acidosis - Hyperkalemia ... Hypoaldosteronism • Acquired ... #differential #
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... infusions) - Metabolic ... acidosis - Hyperkalemia ... Hypoaldosteronism • Acquired ... #differential #
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... acidosis 4) Presentation ... Pulmonary edema, Shock ... High Lactate, Low Potassium ... diagnosis #management #Treatment
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
(renal potassium ... Hypochloremic metabolic ... ratio 0.5%) Differential ... Renal tubular acidosis ... Rhabdomyolysis Treatment
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
AQP-2 gene - Acquired ... Obstructive uropathy, Metabolic ... causes (e.g., hypokalemia ... Treatment is aimed ... Nephrology #Diagnosis #Differential
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Hypotension & Hypovolemia ... Cardiogenic & Septic Shock ... Inborn Errors of Metabolism ... #Differential #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... impairment of cellular metabolism ... sweat) - its metabolism ... ->treatments include ... - Hypovolemia