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diagnosis hepatology algorithm liver injury differential management aclf chronic cirrhosis coagulation comparison deficiencies deficiency druginduced failure gastroenterology hepatorenal hrs nephrology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... • Autoimmune hepatitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Hepatic Artery: Shock ... Medication, Pregnancy, Alcoholic ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Liver Injury (DILI
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Hepatic artery: Shock ... VZV • Trauma: Shock ... ALT Ratios: • Alcoholic ... diagnosis #algorithm #hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... exclude other causes ... : - Acute kidney ... HCV, DILI, HCC, ... Multiorgan failure or shock
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
of Factor IX Acquired ... Liver Disease - Alcohol ... , Viral hepatitis ... DIC - Septic shock ... comparison #diagnosis #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
cirrhosis, severe alcoholic ... hepatitis, or acute ... • Caused by splanchnic ... Treatment Overview ... insult (e.g., alcohol
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