11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) ... Guidelines ACLF ... months without treatment ... Failure Infections Alcohol-Associated ... Failure #Cirrhosis #Hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... ) • Advanced Liver ... Disease - Alcohol ... Acute DIC - Septic shock ... comparison #diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... the secondary or acquired ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Nosocomial or hospital acquired ... Presentation in septic shock ... ciprofloxacin may ... dysfunction or liver ... Diagnosis #Management #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
for HIV, HCV - Alcohol ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... evaluation: not required ... Causes #Workup #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Hepatic artery: Shock ... VZV • Trauma: Shock ... synthetic function may ... ALT Ratios: • Alcoholic ... diagnosis #algorithm #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
• Caused by liver ... Constipation, Alcohol ... Initiate empiric treatment ... building muscle mass ... #hepatology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
nutrients • TPN for treatment ... Liver Disease in ... excluded limb • Treatment ... metronidazole • Alcohol ... Gastroenterology and Hepatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
cirrhosis, severe alcoholic ... sympathetic + ADH activation ... Treatment Overview ... insult (e.g., alcohol ... Hepatorenal #Syndrome #Hepatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... • Secondary (Acquired ... (often termed MAS-HLH ... - Elevated liver ... Diagnosis #Management #Hematology