6 results
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Alcoholism Bone ... Cytogenetics and FISH • Acquired ... Aplastic Anemia ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Alcoholism Bone ... Cytogenetics and FISH • Acquired ... Aplastic Anemia ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Diagnosis: • Pancytopenia ... megaloblastic anemia Treatment ... Can progress to MDS ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... Hypocellular/Hypoplastic MDS ... • Peripheral Pancytopenia ... anemia Treatment ... Anemia #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Infection exposure (l MD ... for HIV, HCV - Alcohol ... evaluation: not required ... ITP, unexplained pancytopenia ... Causes #Workup #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... arsenic compounds, alcohol ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology