13 results
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
and Bone Marrow Failure ... Syndromes with Pancytopenia ... Fanconi Anemia Acquired ... lauraebrown #Pancytopenia ... anemia #diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Alcoholism Bone ... Cytogenetics and FISH • Acquired ... Congenital bone marrow failure ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Alcoholism Bone ... Cytogenetics and FISH • Acquired ... Congenital bone marrow failure ... Diagnosis #Algorithm #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Lung Failure ... Kidney Failure ... Infections Alcohol-Associated ... #Cirrhosis #Hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Liver Disease - Alcohol ... Acute DIC - Septic shock ... comparison #diagnosis #hematology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Nosocomial or hospital acquired ... Presentation in septic shock ... dysfunction or liver failure ... Diagnosis #Management #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
for HIV, HCV - Alcohol ... evaluation: not required ... or if a primary hematologic ... ITP, unexplained pancytopenia ... Causes #Workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... Inherited marrow-failure ... • Peripheral Pancytopenia ... aplastic anemia Treatment ... Anemia #oncology #hematology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Multiorgan failure ... or shock Eligible ... prednisolone #Alcoholic ... Management #Algorithm #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... of multiorgan failure ... lung, and kidney failure ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology