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C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile ... on ABx) → Acute ... Toxic Megacolon, Shock ... post-ABx, but can ... be community-acquired
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Framework Diagnosis ... Immunocompromise Treatment ... • Secondary to Treatment ... diff) • Hospital-Acquired ... Difficile, COVID
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
presents with acute ... Can present: ... fever • Septic shock ... blood cultures Candidiasis ... colonization Candidiasis
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
and esophageal candidiasis ... Viral hepatitis Diagnosis ... acquisition in which no diagnostic ... antibody test) Treatment ... Syndrome #HIV #diagnosis
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity - Diagnosis ... 5) History of acute ... or chronic ingestion ... Pulmonary edema, Shock ... #management #Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
is particularly difficult ... ->treatments include ... before beginning treatment ... cardiac output - Acute ... peritonitis - Acute
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Syndrome (GBS) Acute ... to a preceding infection ... • Most common infection ... and cauda equina TREATMENT ... ventilation is required
IDSA - Approach to Treating a Patient With Diabetic Foot Osteomyelitis
When to consider a trial of
IDSA - Approach ... of nonsurgical treatment ... 48–72 h if on treatment ... ) • Patient can ... high risk for C. difficile
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... Torsemide) • Acute ... myocardial infarction ... • Hypovolemic shock ... Tolvaptan) • Treatment