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Clostridium Difficile Diagnosis and Management Algorithm

IDAGRAM based on most recent guidelines from @IDSAInfo.

 Infographic by IDagram
@ID_agram

#Clostridium
Difficile #Algorithm #Treatment ... Diagnosis #Management #IDSA ... #CDiff
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... can be community-acquired ... Tx Management (IDSA ... Ileus, Megacolon, Shock ... ciab549 #CDI #Cdiff
Outpatient Treatment of with Community-Acquired Pneumonia (CAP)
No comorbidities or risk factors for MRSA or Pseudomonas aeruginosa:
Outpatient Treatment ... with Community-Acquired ... fluoroquinolone #IDSA ... CAP #Community #Acquired ... #Antibiotics #Treatment
IDSA 2017 CDiff Guidelines - Table 7. Potential Treatment Agents for Treatment of the Primary Clostridium difficile
IDSA 2017 CDiff ... Potential Treatment ... Agents for Treatment ... Pharmacology #Management #CDiff
IDSA 2017 CDiff Guidelines - Table 1. Recommendations for the Treatment of Clostridium difficile Infection in Adults

#Management
IDSA 2017 CDiff ... Recommendations for the Treatment
IDSA 2017 CDiff Guidelines - Table 2. Recommendations for the Treatment of Clostridium difficile Infection in Children

#Management
IDSA 2017 CDiff ... Recommendations for the Treatment
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS
Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days)
Preferred
IDSA Recommendations ... antifungals are required ... for effective treatment ... candida #mucosal #IDSA ... #Prevention #Treatment
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Immunocompromise Treatment ... • Secondary to Treatment ... Secondary infection (C diff ... ) • Hospital-Acquired
Treating Condyloma Acuminatum (Genital Warts) - IDSA
Patients with HIV may have larger or more numerous warts,
Genital Warts) - IDSA ... More than one treatment ... option maybe required ... Repeat treatment ... Genital #Warts #idsa
Bacteremia Quick Reference - Treatment Duration

Gram Negative Bacteremia:
 • Avoid: Aminoglycosides and tigecycline
 • Catheters should
Quick Reference - Treatment ... removed in septic shock ... follow up cultures required ... #Bacteremia #Treatment