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IDSA 2017 CDiff Guidelines - Table 1. Recommendations for the Treatment of Clostridium difficile Infection in Adults

#Management
IDSA 2017 CDiff ... Guidelines - Table 1. ... Recommendations for the Treatment ... of Clostridium difficile ... Infection in Adults
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection ... Toxic Megacolon, Shock ... can be community-acquired ... 10 mg/kg IV x 1 ... ciab549 #CDI #Cdiff
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
NMS, serotonin syndrome ... Immunocompromise Treatment ... • Secondary to Treatment ... (C diff) • Hospital-Acquired ... Difficile, COVID
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Diagnosis Framework ... Cardiogenic: Myocardial Infarction ... Abdominal compartment syndrome ... Treatment Goals ... : 1) MAP > 60-65
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
Syndrome (STSS) ... IVIG 1g/kg on day 1, ... day 2 + 3 BIDMC Infectious ... #Syndrome #STSS ... #diagnosis
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
appear in 1-2 days ... • Management: 1. ... progressive inflammatory infection ... • Diagnosis: ... #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Preeclampsia, Eclampsia, Infection ... /Sepsis/Shock, Autoimmune ... : 1. ... : • Infection, ... epilepticus Treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... • Incidence: 1 ... and cauda equina TREATMENT ... ventilation is required ... Guillain #Barre #Syndrome
IDSA - Approach to Treating a Patient With Diabetic Foot Osteomyelitis
When to consider a trial of
IDSA - Approach ... of nonsurgical treatment ... 48–72 h if on treatment ... high risk for C. difficile ... Persistent sepsis syndrome
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... cytokines, such as IL-1 ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management