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C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection ... Toxic Megacolon, Shock ... can be community-acquired ... Ileus, Megacolon, Shock ... ciab549 #CDI #Cdiff
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Framework Diagnosis ... NMS, serotonin syndrome ... Immunocompromise Treatment ... • Secondary to Treatment ... (C diff) • Hospital-Acquired
Hyperglycemia - Differential Diagnosis Algorithm
Diabetes Mellitus:
 • Impaired Glucose Tolerance
 • Type I Diabetes
 • Type
• Cushing's Syndrome ... • Acromegaly Medications ... Corticosteroids • Thiazide diuretics ... Burns, Sepsis) • Shock ... Post Myocardial Infarction
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diagnosis of ... Acute myocardial infarction ... • Hypovolemic shock ... Tolvaptan) • Treatment ... #Pharmacology #Medications
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
essential to determine treatment ... CCB, BB, BRASH syndrome ... thyrotoxicosis), Medications ... , diuretics), Low ... #diagnosis #differential
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Diagnosis Framework ... Failure, Toxins/Medications ... Cardiogenic: Myocardial Infarction ... Abdominal compartment syndrome ... Treatment Goals
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Preeclampsia, Eclampsia, Infection ... /Sepsis/Shock, Autoimmune ... : • Infection, ... Electrolyte abnormality, Medication ... epilepticus Treatment
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
sex • Metabolic syndrome ... • Medications ... (diuretics) Epidemiology ... concomitant infection ... • Discontinue diuretics
IDSA - Approach to Treating a Patient With Diabetic Foot Osteomyelitis
When to consider a trial of
IDSA - Approach ... of nonsurgical treatment ... 48–72 h if on treatment ... not otherwise required ... Persistent sepsis syndrome