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diagnosis toxicology iron management 21hydroxylasedeficiency 21ohd anteriorischemicopticneuropathy aspirin endocrinology ferrous gca genetics giantcellarteritis ophthalmology overdose pathophysiology pediatrics peds poisoning rheumatology
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
Salicylate Toxicity ... no respiratory cause ... ingestion/exposure Symptoms ... Pulmonary edema, Shock ... Salicylate #Aspirin #Toxicity
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
Is visual loss caused ... by AION? ... the optic nerve caused ... Doppler US : halo sign ... Ophthalmology #Diagnosis #Algorithm
Acute Iron Poisoning There are five classically described phases of toxicity: Gastrointestinal phase (~6 hours post-ingestion) -
Abdominal pain, nausea ... post-ingestion) - Symptom ... deterioration Shock ... post-ingestion) - Anion ... and cardiogenic shock
Stages of Iron Toxicity Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... Iron overdose can cause ... dehydration and shock ... Recovery from GI symptoms ... Stage Ill Shock
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... maintains appropriate ion ... Signs/Symptoms/Complications ... vomiting • Late (shock
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