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diagnosis psychiatry genetics inhibitors peds pharmacology sideeffects 21hydroxylasedeficiency 21ohd alzheimersdisease anticholinergics comparison dementia endocrinology geriatrics management opioids praderwilli serotoninnorepinephrine snris
Signs and Symptoms of Toxidromes Sympathomimetic / GABAergic withdrawal Cholinergic Anticholinergic Opioid withdrawal Neuroleptic malignant syndrome Serotonin
Signs and Symptoms ... Neuroleptic malignant syndrome ... Serotonin syndrome ... Sympathomimetics #Diagnosis #Toxicology
Clinical Manifestations of Serotonin Syndrome • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements) • Gastrointestinal: Diarrhea,
Manifestations of Serotonin ... Syndrome • Ophthalmologic ... , Late stages (shock ... #Syndrome #Symptoms ... #spectrum #signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Syndrome: - ... SSRI Withdrawal Syndrome ... #Inhibitors #Pathophysiology ... Psychiatry #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine ... Syndrome - Potentially ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... Psychiatry #Diagnosis #Signs ... #Symptoms
Management of Serotonin Syndrome Identify and stop all serotoninergic medications • Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin ... Syndrome Identify ... normalize vital signs ... then 2 mg q2h if symptoms ... #treatment #toxicology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... #genetics #pathophysiology ... #peds #pediatrics
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... vomiting • Late (shock ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds #pediatrics
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Syndrome: Variable ... #Syndrome #Pathophysiology ... Psychiatry #Diagnosis #Signs ... #Symptoms
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