12 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Juvenile Idiopathic Arthritis ... : Lupus (SLE), Systemic ... Arthritis, Sjögren ... #patterns #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... , Arthritis, myalgia ... constitutional symptoms ... Workup: - ANA ... #table #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
diseases like rheumatoid ... arthritis (RA) ... or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Manifestations: - Arthritis ... Auto-Antibodies: - ANA ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Rheumatoid Arthritis ... knees, shoulders Signs ... & Symptoms: • ... history, exam and ... #management #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... : • Symptoms limited
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... - Autoimmune Rheumatologic ... arthritisSLE ... Symmetrical: • RA • SLE
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Oral aphthae : SLE ... : SLE, Reactive ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis: Systemic rheumatic ... Presentation - Systemic Symptoms ... purpura: strong sign ... LFT • ESR • ANA ... SLE) • Urinalysis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Management Summary ... Extrapulmonary: ankle arthritis ... skin (16-32%): lupus ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms