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diagnosis management comparison hematology myositis sclerosis workup behcet chronic cll cold differential druginduced endocarditis fungal hemeonc hemophagocytic hlh infections infectiousdiseases
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... skin thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... weakness, less systemic ... symptoms, and less ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Autoimmune diseases ... and duration of symptoms ... , Hypotension, shock ... Urticaria #diagnosis #rheumatology ... #comparison #table
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Sclerosis (MS) is an autoimmune-mediated ... neurodegenerative disease ... central nervous system ... Signs and symptoms ... Multiple Sclerosis Treatment
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... Predisposing conditions: Autoimmune ... - Infectious Diseases ... Marantic #diagnosis #table
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... meningitis), MCC CNS symptoms ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... months to years) Systemic ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... acute pulmonary, systemic ... the circulatory system ... Fluconazole SYSTEMIC ... fever • Septic shock
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... microglobulin Treatment
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... Myositis #Myopathy #rheumatology
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