51 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... : • Pathophysiology ... #TLS #diagnosis
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
is a clinical dermatological ... It is also associated ... differentiating between the diagnosis ... #Dermatology #PhysicalExam ... #Video #Clinical
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... gene mutated in all ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
consistent with a diagnosis ... or induced by treatment ... #clinical #video ... #ophthalmology ... #physicalexam #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... lateral sclerosis Pathophysiology ... cellular function Clinical ... conditions listed in differential ... Treatment: - Multidisciplinary
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Medium and large also ... Behcet disease) Differential ... Treatment: • Oral ... inhibitors • Uveitis- Ophthalmology ... #signs #symptoms
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
immune compromise Clinical ... Signs/Symptoms: ... Pathophysiology: ... Coli, but can also ... data • Early treatment
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... estrogen such as ... #Diagnosis #causes
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... Renal Failure Treatment