9 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Iatrogenic) • Liver ... #Causes #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Primary Causes ... renal failure/uremia ... Pruritus #primary #secondary ... #causes
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... guidelines General - Systemic ... sweats, pallor, bruising ... #Limping #NWB #Algorithm ... Pathway #Child #Peds
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... manifestations: from easy bruising ... with leukopenia, anemia ... thrombocytopenia • Liver ... Diagnosis #Management #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
• Cholestatic liver ... renal failure/uremia ... #Pruritus #secondary ... #systemic #generalized ... #causes
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... disease • Liver ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Systemic causes ... include diabetes, anemia ... hyperthyroidism, peripheral ischemia ... Seen in liver disease ... Arising from the
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... of the immune system ... STX11, STXBP2 • Secondary ... - Cytopenias (anemia ... - Elevated liver