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diagnosis differential causes lfts transaminitis aclf aih alcoholic chronic cirrhosis dili druginduced failure function gastroenterology hbv hepatitisb hepatocellular hepbv indications
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... injury - Viral ... Hepatitis - Autoimmune ... #Differential #Hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... 20x normal - Acute ... #Patterns #Liver ... #Injury #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #Injury #Differential ... #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... dechallenge • Acute ... steatosis • Autoimmune ... #Algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... • Vascular: Ischemic ... Other: NAFLD, Autoimmune ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Chronic Viral Hepatitis ... Hepatopathy • Acute ... Viral Hepatitis ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Other • ATN: Ischemia ... Medication, Infection, Autoimmune ... nephrology #causes #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... : Autoimmune hepatitis ... #injury #hepatitis ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... Viral Hepatitis ... Procedures Management ... Failure #Cirrhosis #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Autoimmune ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
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