9 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... 20x normal - Acute ... 5-10x normal - Chronic ... Patterns #Liver #Injury ... #hepatology #LFTs
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Drug-Induced Liver Injury ... #Chronic #Liver ... Failure #Cirrhosis #Hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Cirrhosis • Chronic ... Hepatopathy • Acute ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... Differential #Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... disease, Hepatic ischaemia ... dechallenge • Acute ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... Algorithm • ... Chronic Hepatitis ... #Management #Treatment ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... > 2 • NASH, Chronic ... > 3 • Chronic ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... with severe liver injury ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... - Symptoms of chronic ... pattern of liver injury ... regarding need for treatment ... #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... injury with serum ... #Management #Algorithm ... #hepatology