10 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
• NAFLD • Cirrhosis ... Hepatopathy • Acute ... (>1000): • DILI ... #Diagnosis #hepatology ... #transaminitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
20x normal - Acute ... CMV), Alcoholic cirrhosis ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminases / Transaminitis ... - Differential ... • Iatrogenic: DILI ... See Updated Schema ... Diagnosis #causes #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... dechallenge • Acute ... • Autoimmune hepatitis ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... for Transaminitis ... Drugs, Viral, Ischemia ... Congenital, Others, Cirrhosis ... #hepatology #LiverFunctionTests
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... : < 1 • Cirrhosis ... #differential # ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
>1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... Veno-occlusive disease - Acute ... associated with bowel ischemia ... #Diagnosis #hepatology