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diagnosis differential liver lfts acute common dili druginduced gestationalage growthrestriction hematology hepatocellular hypogammaglobulinemia immunodeficiency immunology liverenzymes management obgyn obstetrics pregnancy
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • Autoimmune ... hepatitis • Drugs ... Others #LFTs #Hepatology ... #Causes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Other: NAFLD, Autoimmune ... #Acute #algorithm ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... HEV, EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... steatosis • Autoimmune ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Causes of Intrauterine Growth Restriction / Small for Gestational Age - Differential Diagnosis Algorithm Fetal Factors: -
Causes of Intrauterine ... - Placental Ischemia ... mellitus • Autoimmune ... Smoking • Alcohol ... GestationalAge #SGA
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... : Autoimmune hepatitis ... ALT Ratios: • Alcoholic ... #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... Liver diseases and hepatitis ... ) • Low serum IgA ... DDX - Other causes ... Malignancies • Chronic
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