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differential liver lfts causes injury transaminitis ascites chronic hematology management saag abnormal aclf albumin chemistry diffuse dili druginduced elevated failure
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
20x normal - Acute ... cirrhosis, Portal ... AST:ALT > 2.5 - Alcoholic ... Liver #Injury #hepatology ... #differential #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... Bile Ducts • PSC ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Drugs, Viral, Ischemia ... , PSC, Alcoholic ... Congenital, Others, Cirrhosis ... #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
- Differential Diagnosis ... HSV • Toxic: Alcohol ... Malignancy, 1° PBC ... #Differential #Diagnosis ... #algorithm #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
- Differential Diagnosis ... Algorithm Malignant ... Inflammatory • Alcoholic ... Primary Biliary Cirrhosis ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular ... , PBC, PSC, IgG4 ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... Hepatopathy • Acute ... Viral Hepatitis ... liver injury) • Ischemic ... #hepatology #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... #Hepatology #gastroenterology ... #management #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... Tuberculosis • Hepatitis ... Fatigue • Acute ... #Hematology #Oncology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... viremia or have cirrhosis ... • Monitor: CBC ... #Treatment #Hepatology
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