17 results
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Drugs • AIH ... hepatitis • Drugs ... Others #LFTs #Hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
20x normal - Acute ... Infection (EBV/CMV), Alcoholic ... AST:ALT > 2.5 - Alcoholic ... Liver #Injury #hepatology ... #differential #diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Algorithm for Transaminitis ... Drugs, Viral, Ischemia ... kwburak #LFTs #Elevated ... #diagnosis #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
of Alcoholic Hepatitis ... factors • Possible ischemic ... #diagnosis #Alcoholic ... #Hepatitis #AH ... #hepatology #criteria
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Hepatopathy • Acute ... Viral Hepatitis ... liver injury) • Ischemic ... #hepatology #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... HSV • Toxic: Alcohol ... Medication, Pregnancy, Alcoholic ... #Differential #Diagnosis ... #algorithm #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... factors - Possible ischemic ... #Diagnosis #Hepatology ... #AIH
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... Injury: • Early acute ... hepatitisIschemic ... hepatitisAcute ... fever) • Drugs (alcohol
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... IgG typically elevated ... , AIH diagnosis ... #AIH #Diagnosis ... #Management #Hepatology