9 results
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... hepatitis • Drugs ... • Others #LFTs ... #Hepatology #LiverEnzymes
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Infection (EBV/CMV), Alcoholic ... AST:ALT > 2.5 - Alcoholic ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... Differential Diagnosis ... liver injury) • Ischemic ... Diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #Elevated #Abnormal ... #diagnosis #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... a cytoplasmic enzyme ... • Ischemic hepatitis ... fever) • Drugs (alcohol ... #differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... ALT Ratios: • Alcoholic ... Source of Liver Enzyme ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Liver #Enzymes ... #Differential #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... specificity to elevated ... ALT Ratios: • Alcoholic ... Source of Liver Enzyme ... #hepatology