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diagnosis liver lfts transaminitis acute causes abnormal aclf autoimmune chemistry chronic cirrhosis dehydrogenase dili druginduced failure function gastroenterology hepatocellular interpretation
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... AST:ALT > 2.5 - Alcoholic ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Drugs • AIH ... hepatitis • Drugs ... Others #LFTs #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Drugs, Viral, Ischemia ... kwburak #LFTs #Elevated ... #diagnosis #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - Differential ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... #Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... HSV • Toxic: Alcohol ... Causes #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... survival in severe AH ... #Hepatitis #Management ... #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... • Ischemic hepatitis ... Hepatocellular Injury ... fever) • Drugs (alcohol ... #differential #
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Alcoholic Hepatitis - Summary Overview - Epidemiology - Pathophysiology - Clinical Features - Labs - Diagnosis - Differential Diagnosis - Treatment Sarah Onorato @sonorato11 #Alcoholic
Alcoholic Hepatitis ... - Diagnosis - Differential ... #Hepatitis #hepatology ... #diagnosis #algorithm ... #management
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