6 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
20x normal - Acute ... Infection (EBV/CMV), Alcoholic ... 5-10x normal - Chronic ... AST:ALT > 2.5 - Alcoholic ... Liver #Injury #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
disease, Hepatic ischaemia ... dechallenge • Acute ... disorder (e.g. ascites ... ), Chronic hepatitis ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Failure #Cirrhosis #Hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Cirrhosis - Alcoholic ... hepatitis - Cardiac ... Veno-occlusive disease - Acute ... associated with bowel ischemia ... Differential #Diagnosis #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... blood, urine and ascites ... : - Acute kidney ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #hepatology