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diagnosis differential injury hematology lfts transaminitis laboratory management arthritis ascites disease interpretation rheumatology serology acute alcoholic chemistry common cvid diffuse
Hepatitis B Virus Serology and Interpretation HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe - Acute
B - Chronic hepatitis ... replication - Inactive HBV ... carrier state (low HBV ... #HBV #Serology ... diagnosis #laboratory #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... serologic evidence of hepatitis ... HAV immunity; Liver ... Chronic Hepatitis ... #HepatitisB #HBV
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
, HCV, HEV, EBV, ... Trauma: Shock liver ... • Autoimmune hepatitis ... Transaminases #hepatitis ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
, HBV, HCV, HEV, ... Hepatic ischaemia ... hepatitis fibrosis ... • Autoimmune hepatitis ... #hepatology
Interpretation of Hepatitis B Serologies HBsAg - HBcAb (total) - HBcAb (IgM) - HBsAb Susceptible to HBV Immune
Interpretation of Hepatitis ... Chronic HBV Resolved ... BrighamChiefs #HepatitisB ... serology #diagnosis #hepatology ... interpreation #testing
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Hepatitis > ... - Acute Viral Hepatitis ... , Toxic Hepatitis ... 5-10x normal - Chronic ... #Injury #hepatology
Hepatitis B Disease Progression Timeline • > 90% of infected children progress to chronic disease (<5%
Hepatitis B Disease ... HBV-infected individuals ... of chronic HBV-infected ... developing cirrhosis #HepatitisB ... Epidemiology #HepB #HBV
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
, HBV, HCV, HEV, ... EBV, HSV, CMV, ... Autoimmune: Autoimmune hepatitis ... viral hepatitis ... #injury #hepatitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... , CMV, HSV • Toxic ... NAFLD, Autoimmune hepatitis ... Pregnancy, Alcoholic Hepatitis ... Sepsis, Viral Hepatitis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... CMV, HSV, VZV ... • Vascular: Ischemic ... #algorithm #Transaminitis ... #LFTs #hepatitis
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